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Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line.

The NIH 3T3 mouse cell line is widely used as a recipient of DNA from tumors to demonstrate the presence of transforming oncogenes. We show that these cells produce transformed foci spontaneously if kept in the confluent state for more than 10 days. The formation of foci depends on the type and conc...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Rubin, H, Xu, K
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2928308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1860
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