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Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line.

The NIH 3T3 mouse cell line is widely used as a recipient of DNA from tumors to demonstrate the presence of transforming oncogenes. We show that these cells produce transformed foci spontaneously if kept in the confluent state for more than 10 days. The formation of foci depends on the type and conc...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Rubin, H, Xu, K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2928308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1860
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