Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line.
The NIH 3T3 mouse cell line is widely used as a recipient of DNA from tumors to demonstrate the presence of transforming oncogenes. We show that these cells produce transformed foci spontaneously if kept in the confluent state for more than 10 days. The formation of foci depends on the type and conc...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1989
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2928308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1860 |
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