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Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting

Kinetic control of macromolecular interactions plays key roles in biological regulation. An example of such control occurs in cotranslational protein targeting by the signal recognition particle (SRP), during which the SRP RNA and the cargo both accelerate complex assembly between the SRP and SRP re...

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Bibliografiske detaljer
Main Authors: Shen, Kuang, Shan, Shu-ou
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867919/
https://ncbi.nlm.nih.gov/pubmed/20385832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002968107
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