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Activated GTPase movement on an RNA scaffold drives cotranslational protein targeting

Roughly one third of the proteome is initially destined for the eukaryotic endoplasmic reticulum or the bacterial plasma membrane(1). The proper localization of these proteins is mediated by a universally conserved protein targeting machinery, the signal recognition particle (SRP), which recognizes...

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書目詳細資料
Main Authors: Shen, Kuang, Arslan, Sinan, Akopian, David, Ha, Taekjip, Shan, Shu-ou
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531814/
https://ncbi.nlm.nih.gov/pubmed/23235881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11726
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