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Activated GTPase movement on an RNA scaffold drives cotranslational protein targeting

Roughly one third of the proteome is initially destined for the eukaryotic endoplasmic reticulum or the bacterial plasma membrane(1). The proper localization of these proteins is mediated by a universally conserved protein targeting machinery, the signal recognition particle (SRP), which recognizes...

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Detalhes bibliográficos
Main Authors: Shen, Kuang, Arslan, Sinan, Akopian, David, Ha, Taekjip, Shan, Shu-ou
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531814/
https://ncbi.nlm.nih.gov/pubmed/23235881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11726
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