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Entropic mechanism of large fluctuation in allosteric transition
A statistical mechanical model of allosteric transitions in proteins is developed by extending the structure-based model of protein folding to cases of multiple native conformations. The partition function is calculated exactly within the model and the free-energy surface reflecting allostery is der...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867861/ https://ncbi.nlm.nih.gov/pubmed/20385843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912978107 |
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