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Entropic mechanism of large fluctuation in allosteric transition

A statistical mechanical model of allosteric transitions in proteins is developed by extending the structure-based model of protein folding to cases of multiple native conformations. The partition function is calculated exactly within the model and the free-energy surface reflecting allostery is der...

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Bibliografski detalji
Glavni autori: Itoh, Kazuhito, Sasai, Masaki
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867861/
https://ncbi.nlm.nih.gov/pubmed/20385843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912978107
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