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Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains
Polyubiquitin chains mediate a variety of biological processes, ranging from proteasomal targeting to inflammatory signaling and DNA repair. Their functional diversity is in part due to their ability to adopt distinct conformations, depending on how the ubiquitin moieties within the chain are linked...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867854/ https://ncbi.nlm.nih.gov/pubmed/20385835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908764107 |
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