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Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains

Polyubiquitin chains mediate a variety of biological processes, ranging from proteasomal targeting to inflammatory signaling and DNA repair. Their functional diversity is in part due to their ability to adopt distinct conformations, depending on how the ubiquitin moieties within the chain are linked...

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Detalhes bibliográficos
Main Authors: Zhao, Shengkai, Ulrich, Helle D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867854/
https://ncbi.nlm.nih.gov/pubmed/20385835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908764107
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