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Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex

Atypical Rho-guanine nucleotide exchange factors (Rho-GEFs) that contain Dock homology regions (DHR-1 and DHR-2) are expressed in a variety of tissues; however, their functions and mechanisms of action remain unclear. We identify key conserved amino acids in the DHR-2 domain that are critical for th...

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Detalhes bibliográficos
Main Authors: Namekata, Kazuhiko, Harada, Chikako, Taya, Choji, Guo, Xiaoli, Kimura, Hideo, Parada, Luis F., Harada, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867726/
https://ncbi.nlm.nih.gov/pubmed/20368433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914514107
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