Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts

Hypothyroidism and thyrotoxicosis are each associated with an increased risk of fracture. Although thyroxine (T4) is the predominant circulating thyroid hormone, target cell responses are determined by local intracellular availability of the active hormone 3,5,3′-L-triiodothyronine (T3), which is ge...

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Detalhes bibliográficos
Main Authors: Bassett, J. H. Duncan, Boyde, Alan, Howell, Peter G. T., Bassett, Richard H., Galliford, Thomas M., Archanco, Marta, Evans, Holly, Lawson, Michelle A., Croucher, Peter, St. Germain, Donald L., Galton, Valerie Anne, Williams, Graham R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867713/
https://ncbi.nlm.nih.gov/pubmed/20368437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911346107
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