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Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants

The neurofibromatosis type 2 (NF2) tumor-suppressor protein Merlin is a member of the ERM family of proteins that links the cytoskeleton to the plasma membrane. In humans, mutations in the NF2 gene cause neurofibromatosis type-2 (NF2), a cancer syndrome characterized by the development of tumors of...

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Main Authors: Benseñor, Lorena B., Barlan, Kari, Rice, Sarah E., Fehon, Richard G., Gelfand, Vladimir I.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867680/
https://ncbi.nlm.nih.gov/pubmed/20368450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907389107
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