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The microtubule-binding protein ensconsin is an essential cofactor of kinesin-1
Kinesin-1 is a major microtubule motor that drives transport of numerous cellular cargoes toward the plus-ends of microtubules. In the cell, kinesin-1 exists primarily in an inactive, autoinhibited state [1, 2], and motor activation is thought to occur upon binding to cargo through the C-terminus [3...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580027/ https://ncbi.nlm.nih.gov/pubmed/23394833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.01.008 |
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