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Role of kinesin-1–based microtubule sliding in Drosophila nervous system development

The plus-end microtubule (MT) motor kinesin-1 is essential for normal development, with key roles in the nervous system. Kinesin-1 drives axonal transport of membrane cargoes to fulfill the metabolic needs of neurons and maintain synapses. We have previously demonstrated that kinesin-1, in addition...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Winding, Michael, Kelliher, Michael T., Lu, Wen, Wildonger, Jill, Gelfand, Vladimir I.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003282/
https://ncbi.nlm.nih.gov/pubmed/27512046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522416113
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