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Influence of PARP-1 Polymorphisms in Patients after Traumatic Brain Injury

Poly(ADP-ribose) polymerase-1 (PARP-1) plays an important role in the cellular response to stress and DNA damage. However, excessive activity of PARP-1 exacerbates brain injury via NAD(+) depletion and energy failure. The purpose of this study was to determine if tagging single nucleotide polymorphi...

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Detalhes bibliográficos
Main Authors: Sarnaik, Ajit A., Conley, Yvette P., Okonkwo, David O., Barr, Taura L., Fink, Ericka L., Szabo, Csaba, Kochanek, Patrick M., Clark, Robert S.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867630/
https://ncbi.nlm.nih.gov/pubmed/19925161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.1171
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