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Quantification of Poly(ADP-ribose)-Modified Proteins in Cerebrospinal Fluid from Infants and Children after Traumatic Brain Injury

Poly-ADP-ribosylation (PAR) of proteins by poly(ADP-ribose) polymerases (PARP) occurs after experimental traumatic brain injury (TBI) and modulates neurological outcome. Several promising pharmacological PARP inhibitors have been developed for use in humans, but there is currently no clinically rele...

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Detalhes bibliográficos
Main Authors: Fink, Ericka L., Lai, Yichen, Zhang, Xiaopeng, Janesko-Feldman, Keri, Adelson, P. David, Szabó, Csaba, Berger, Rachel P., Sarnaik, Ajit A., Kochanek, Patrick M., Clark, Robert S. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2560585/
https://ncbi.nlm.nih.gov/pubmed/18506195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.52
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