The switch of intestinal Slc26 exchangers from anion absorptive to HCO(3)(−) secretory mode is dependent on CFTR anion channel function

CFTR has been recognized to function as both an anion channel and a key regulator of Slc26 anion transporters in heterologous expression systems. Whether this regulatory relationship between CFTR and Slc26 transporters is seen in native intestine, and whether this effect is coupled to CFTR transport...

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Autori principali: Singh, Anurag Kumar, Riederer, Brigitte, Chen, Mingmin, Xiao, Fang, Krabbenhöft, Anja, Engelhardt, Regina, Nylander, Olof, Soleimani, Manoocher, Seidler, Ursula
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
Soggetti:
Membrane Transporters, Ion Channels and Pumps
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867396/
https://ncbi.nlm.nih.gov/pubmed/20164375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00454.2009
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