The switch of intestinal Slc26 exchangers from anion absorptive to HCO(3)(−) secretory mode is dependent on CFTR anion channel function

CFTR has been recognized to function as both an anion channel and a key regulator of Slc26 anion transporters in heterologous expression systems. Whether this regulatory relationship between CFTR and Slc26 transporters is seen in native intestine, and whether this effect is coupled to CFTR transport...

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Detalhes bibliográficos
Main Authors: Singh, Anurag Kumar, Riederer, Brigitte, Chen, Mingmin, Xiao, Fang, Krabbenhöft, Anja, Engelhardt, Regina, Nylander, Olof, Soleimani, Manoocher, Seidler, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Membrane Transporters, Ion Channels and Pumps
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867396/
https://ncbi.nlm.nih.gov/pubmed/20164375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00454.2009
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