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Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility

Glycosphingolipids GM3 and GM2 inhibit (i) cell growth through inhibition of tyrosine kinase associated with growth factor receptor (GFR), (ii) cell adhesion/motility through inhibition of integrin-dependent signaling via Src kinases, or (iii) both cell growth and motility by blocking “cross-talk” b...

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Detalhes bibliográficos
Autor principal: Hakomori, Sen-itiroh
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867360/
https://ncbi.nlm.nih.gov/pubmed/19874824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.10.065
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