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Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility

Glycosphingolipids GM3 and GM2 inhibit (i) cell growth through inhibition of tyrosine kinase associated with growth factor receptor (GFR), (ii) cell adhesion/motility through inhibition of integrin-dependent signaling via Src kinases, or (iii) both cell growth and motility by blocking “cross-talk” b...

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Bibliografiska uppgifter
Huvudupphovsman: Hakomori, Sen-itiroh
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867360/
https://ncbi.nlm.nih.gov/pubmed/19874824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.10.065
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