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β-Arrestin–dependent activation of Ca(2+)/calmodulin kinase II after β(1)–adrenergic receptor stimulation

Ca(2+)/calmodulin kinase II (CaMKII) plays an important role in cardiac contractility and the development of heart failure. Although stimulation of β(1)–adrenergic receptors (ARs) leads to an increase in CaMKII activity, the molecular mechanism by which β(1)-ARs activate CaMKII is not completely und...

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Detalhes bibliográficos
Main Authors: Mangmool, Supachoke, Shukla, Arun K., Rockman, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867304/
https://ncbi.nlm.nih.gov/pubmed/20421423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911047
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