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Destabilization of an alpha-helix-bundle protein by helix dipoles.

The finite difference Poisson-Boltzmann method is used to calculate the electrostatic work of assembling the four alpha-helices of Themiste dyscritum hemerythrin to form the protein's observed antiparallel helical bundle. The calculations account for the interaction of each helix dipole with th...

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Bibliografische gegevens
Hoofdauteurs: Gilson, M K, Honig, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC286730/
https://ncbi.nlm.nih.gov/pubmed/2922396
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