Destabilization of an alpha-helix-bundle protein by helix dipoles.
The finite difference Poisson-Boltzmann method is used to calculate the electrostatic work of assembling the four alpha-helices of Themiste dyscritum hemerythrin to form the protein's observed antiparallel helical bundle. The calculations account for the interaction of each helix dipole with the hig...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2922396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.5.1524 |
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