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Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
The roles of autoimmune regulator (Aire)–expressing medullary thymic epithelial cells (mTECs) in the organization of the thymic microenvironment for establishing self-tolerance are enigmatic. We sought to monitor the production and maintenance of Aire-expressing mTECs by a fate-mapping strategy in w...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867289/ https://ncbi.nlm.nih.gov/pubmed/20404099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092144 |
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