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Synthesis of a Monophosphoryl Derivative of Escherichia coli Lipid A and Its Efficient Coupling to a Tumor-Associated Carbohydrate Antigen

Monophosphoryl lipid A is a safe and potent immunostimulant and vaccine adjuvant, which is potentially useful for the development of effective carbohydrate-based conjugate vaccines. This paper presented a convergent and efficient synthesis of a monophosphoryl derivative of E. coli lipid A having an...

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Detalhes bibliográficos
Main Authors: Tang, Shouchu, Wang, Qianli, Guo, Zhongwu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867242/
https://ncbi.nlm.nih.gov/pubmed/19943286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200902153
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