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Synthesis of a Monophosphoryl Derivative of Escherichia coli Lipid A and Its Efficient Coupling to a Tumor-Associated Carbohydrate Antigen
Monophosphoryl lipid A is a safe and potent immunostimulant and vaccine adjuvant, which is potentially useful for the development of effective carbohydrate-based conjugate vaccines. This paper presented a convergent and efficient synthesis of a monophosphoryl derivative of E. coli lipid A having an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867242/ https://ncbi.nlm.nih.gov/pubmed/19943286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200902153 |
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