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Immuno-Stimulatory Activity of Escherichia coli Mutants Producing Kdo(2)-Monophosphoryl-Lipid A or Kdo(2)-Pentaacyl-Monophosphoryl-Lipid A

Lipid A is the active center of lipopolysaccharide which also known as endotoxin. Monophosphoryl-lipid A (MPLA) has less toxicity but retains potent immunoadjuvant activity; therefore, it can be developed as adjuvant for improving the strength and duration of the immune response to antigens. However...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Biwen, Han, Yaning, Li, Ye, Li, Yanyan, Wang, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692390/
https://ncbi.nlm.nih.gov/pubmed/26710252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144714
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