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Acceleration of crossbridge kinetics by protein kinase A phosphorylation of cardiac myosin binding protein C modulates cardiac function
Normal cardiac function requires dynamic modulation of contraction. β(1) adrenergic-induced protein kinase A (PKA) phosphorylation of cardiac myosin binding protein C (cMyBP-C) may regulate crossbridge kinetics to modulate contraction. We tested this idea with mechanical measurements and echocardiog...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867079/ https://ncbi.nlm.nih.gov/pubmed/18802026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.177683 |
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