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Ablation of Myosin-Binding Protein-C Accelerates Force Development in Mouse Myocardium

Myosin-binding protein-C (MyBP-C) is a thick filament-associated protein that binds tightly to myosin. Given that cMyBP-C may act to modulate cooperative activation of the thin filament by constraining the availability of myosin cross-bridges for binding to actin, we investigated the role of MyBP-C...

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Detalhes bibliográficos
Main Authors: Stelzer, Julian E., Fitzsimons, Daniel P., Moss, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459529/
https://ncbi.nlm.nih.gov/pubmed/16513777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078147
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