Protein kinase A changes calcium sensitivity but not crossbridge kinetics in human cardiac myofibrils

We investigated the effect of PKA treatment (1 U/ml) on the mechanical properties of isolated human cardiac myofibrils. PKA treatment was associated with significant incorporation of radiolabeled phosphate into several sarcomeric proteins including troponin I and myosin binding protein C and was als...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Walker, John S., Walker, Lori A., Margulies, Ken, Buttrick, Peter, de Tombe, Pieter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2011
Gaiak:
Muscle Mechanics and Ventricular Function
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129926/
https://ncbi.nlm.nih.gov/pubmed/21498779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00838.2010
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