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Protein kinase A changes calcium sensitivity but not crossbridge kinetics in human cardiac myofibrils
We investigated the effect of PKA treatment (1 U/ml) on the mechanical properties of isolated human cardiac myofibrils. PKA treatment was associated with significant incorporation of radiolabeled phosphate into several sarcomeric proteins including troponin I and myosin binding protein C and was als...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129926/ https://ncbi.nlm.nih.gov/pubmed/21498779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00838.2010 |
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