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An enriched structural kinase database to enable kinome-wide structure-based analyses and drug discovery

The development of a kinase structural database, the kinase knowledge base (KKB), is described. It covers all human kinase domain structures that have been deposited in the Protein Data Bank. All structures are renumbered using a common scheme, which enables efficient cross-comparisons and multiple...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brooijmans, Natasja, Chang, Yu-Wei, Mobilio, Dominick, Denny, Rajiah A, Humblet, Christine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Subscription Services, Inc., A Wiley Company 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867016/
https://ncbi.nlm.nih.gov/pubmed/20135687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.355
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