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An enriched structural kinase database to enable kinome-wide structure-based analyses and drug discovery

The development of a kinase structural database, the kinase knowledge base (KKB), is described. It covers all human kinase domain structures that have been deposited in the Protein Data Bank. All structures are renumbered using a common scheme, which enables efficient cross-comparisons and multiple...

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Detalhes bibliográficos
Main Authors: Brooijmans, Natasja, Chang, Yu-Wei, Mobilio, Dominick, Denny, Rajiah A, Humblet, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867016/
https://ncbi.nlm.nih.gov/pubmed/20135687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.355
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