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Repression of β-catenin signaling by PPARγ ligands
Aberrant activation of the Wnt/β-catenin signaling pathway plays a crucial role in oncogenesis of various human malignancies. It has been demonstrated that there is a direct interaction between β-catenin and PPARγ. Here we examined the effects of fifteen reported PPAR ligands in a reporter gene assa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866743/ https://ncbi.nlm.nih.gov/pubmed/20303941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.03.010 |
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