COUP-TFII acts downstream of Wnt/β-catenin signal to silence PPARγ gene expression and repress adipogenesis

Wnt signaling through β-catenin and TCF maintains preadipocytes in an un-differentiated proliferative state; however, the molecular pathway has not been completely defined. By integrating gene expression microarray, chromatin immunoprecipitation-chip, and cell-based experimental approaches, we show...

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Detalhes bibliográficos
Main Authors: Okamura, Masashi, Kudo, Hiromi, Wakabayashi, Ken-ichi, Tanaka, Toshiya, Nonaka, Aya, Uchida, Aoi, Tsutsumi, Shuichi, Sakakibara, Iori, Naito, Makoto, Osborne, Timothy F., Hamakubo, Takao, Ito, Sadayoshi, Aburatani, Hiroyuki, Yanagisawa, Masashi, Kodama, Tatsuhiko, Sakai, Juro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667001/
https://ncbi.nlm.nih.gov/pubmed/19307559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901676106
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