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Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia
Congenital diaphragmatic hernia (CDH), a life-threatening anomaly, is a major cause of pediatric mortality. Although the disease was described >350 years ago, the etiology of CDH is poorly understood. Here, we show that tissue-specific null mutants of COUP-TFII exhibit Bochdalek-type CDH, the mos...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283449/ https://ncbi.nlm.nih.gov/pubmed/16251273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507832102 |
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