Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia

Congenital diaphragmatic hernia (CDH), a life-threatening anomaly, is a major cause of pediatric mortality. Although the disease was described >350 years ago, the etiology of CDH is poorly understood. Here, we show that tissue-specific null mutants of COUP-TFII exhibit Bochdalek-type CDH, the mos...

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Main Authors: You, Li-Ru, Takamoto, Norio, Yu, Cheng-Tai, Tanaka, Toshiya, Kodama, Tatsuhiko, DeMayo, Francesco J., Tsai, Sophia Y., Tsai, Ming-Jer
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283449/
https://ncbi.nlm.nih.gov/pubmed/16251273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507832102
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