Highly attenuated vaccinia virus mutants for the generation of safe recombinant viruses.

An attenuated vaccinia virus mutant with specific genetic lesions has been used to develop a vehicle for safer live recombinant virus vaccines. The mutant virus 48-7 has an 8-MDa deletion starting 2.2 MDa from the left end of the viral genome and point mutations in the gene encoding the 14-kDa fusio...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Rodriguez, D, Rodriguez, J R, Rodriguez, J F, Trauber, D, Esteban, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286673/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2784004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.4.1287
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!