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Cullin 5 Regulates Cortical Layering by Modulating the Speed and Duration of Dab1-Dependent Neuronal Migration

The multilayered mammalian neocortex develops by the coordinated immigration and differentiation of cells that are produced at distant sites. Correct layering requires an extracellular protein, Reelin (Reln), an intracellular signaling molecule, Disabled-1 (Dab1), and an E3 ubiquitin ligase, Cullin-...

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Detalhes bibliográficos
Main Authors: Simó, Sergi, Jossin, Yves, Cooper, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866641/
https://ncbi.nlm.nih.gov/pubmed/20410119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0035-10.2010
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