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Cullin 5 Regulates Cortical Layering by Modulating the Speed and Duration of Dab1-Dependent Neuronal Migration
The multilayered mammalian neocortex develops by the coordinated immigration and differentiation of cells that are produced at distant sites. Correct layering requires an extracellular protein, Reelin (Reln), an intracellular signaling molecule, Disabled-1 (Dab1), and an E3 ubiquitin ligase, Cullin-...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866641/ https://ncbi.nlm.nih.gov/pubmed/20410119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0035-10.2010 |
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