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Cullin 5 Regulates Cortical Layering by Modulating the Speed and Duration of Dab1-Dependent Neuronal Migration

The multilayered mammalian neocortex develops by the coordinated immigration and differentiation of cells that are produced at distant sites. Correct layering requires an extracellular protein, Reelin (Reln), an intracellular signaling molecule, Disabled-1 (Dab1), and an E3 ubiquitin ligase, Cullin-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Simó, Sergi, Jossin, Yves, Cooper, Jonathan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866641/
https://ncbi.nlm.nih.gov/pubmed/20410119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0035-10.2010
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