INCREASED IMMUNOGENICITY OF HIV-1 p24 AND gp120 FOLLOWING IMMUNIZATION WITH gp120/p24 FUSION PROTEIN VACCINE EXPRESSING α-GAL EPITOPES

Developing an effective HIV-1 vaccine will require strategies to enhance antigen presentation to the immune system. In a previous study we demonstrated a marked increase in immunogenicity of the highly glycosylated HIV-1 gp120 protein following enzymatic addition of α-gal epitopes to the carbohydrat...

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Detalhes bibliográficos
Main Authors: Abdel-Motal, Ussama M., Wang, Shixia, Awad, Amany, Lu, Shan, Wigglesworth, Kim, Galili, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866524/
https://ncbi.nlm.nih.gov/pubmed/20034607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.12.015
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