The Ability to Promote Efflux via ABCA1 Determines the Capacity of Serum Specimens with Similar HDL-C to Remove Cholesterol from Macrophages

OBJECTIVES: We measured efflux from macrophages to apoB–depleted serum from 263 specimens and found instances where serum having similar HDL-C differed in their efflux capacity. Thus we wanted to elucidate why efflux capacity could be independent of total HDL-C or apoA-I. METHODS AND RESULTS: To und...

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Hlavní autoři: de la Llera-Moya, Margarita, Drazul-Schrader, Denise, Asztalos, Bela F., Cuchel, Marina, Rader, Daniel J., Rothblat, George H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866499/
https://ncbi.nlm.nih.gov/pubmed/20075420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.199158
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