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Aprotinin Concentration Varies Significantly According to Cardiopulmonary Bypass Conditions

OBJECTIVES: Although aprotinin is partially excreted unchanged in the urine, its primary site of metabolism is in the renal lysosomes following proximal tubule resorption. This study tested the hypothesis that plasma aprotinin concentration varies with cardiopulmonary bypass conditions. METHODS: Thi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Okamura, Toru, Ishibashi, Nobuyuki, Iwata, Yusuke, Zurakowski, David, Jonas, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866497/
https://ncbi.nlm.nih.gov/pubmed/19454564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0267659109105080
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