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Using Activated Clotting Time to Estimate Intraoperative Aprotinin Concentration

BACKGROUND: Use of aprotinin during cardiopulmonary bypass may be associated with renal dysfunction due to renal excretion of excess drug. We hypothesized that the difference between standard celite activated clotting time (ACT), which is prolonged by aprotinin and kaolin ACT, could provide an estim...

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Main Authors: Iwata, Yusuke, Okamura, Toru, Zurakowski, David, Jonas, Richard A.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852100/
https://ncbi.nlm.nih.gov/pubmed/20093334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0267659109358471
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