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Optimal dose of aprotinin for neuroprotection and renal function in a piglet survival model

OBJECTIVE: The efficacy of aprotinin in reducing blood loss after CPB is well established although its neuroprotective potential is less well known. Furthermore, there is controversy regarding optimal dosing and possible renal complications. METHODS: 54 piglets were randomized to one of three CPB gr...

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Bibliografiska uppgifter
Huvudupphovsmän: Iwata, Yusuke, Okamura, Toru, Ishibashi, Nobuyuki, Zurakowski, David, Lidov, Hart G. W., Jonas, Richard A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846518/
https://ncbi.nlm.nih.gov/pubmed/19464474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2008.06.049
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