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Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains

Toll-like receptors (TLRs) are innate immune pattern-recognition receptors endowed with the capacity to detect microbial pathogens based on pathogen-associated molecular patterns. The understanding of the molecular principles of ligand recognition by TLRs has been greatly accelerated by recent struc...

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Detalhes bibliográficos
Main Authors: Kubarenko, Andriy V, Ranjan, Satish, Colak, Elif, George, Julie, Frank, Martin, Weber, Alexander N R
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866280/
https://ncbi.nlm.nih.gov/pubmed/20073080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.333
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