Loading...
Mcl-1–Bim complexes accommodate surprising point mutations via minor structural changes
Mcl-1 is an antiapoptotic Bcl-2-family protein that protects cells against death. Structures of Mcl-1, and of other anti-apoptotic Bcl-2 proteins, reveal a surface groove into which the α-helical BH3 regions of certain proapoptotic proteins can bind. Despite high overall structural conservation, dif...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866276/ https://ncbi.nlm.nih.gov/pubmed/20066663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.329 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|