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A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

Oxidative modification of low density lipoprotein (LDL) has been implicated as a factor in the generation of macrophage-derived foam cells in vitro and in vivo. However, the exact mechanism of LDL oxidation has not been established. The present studies show that cellular lipoxygenase activity is inv...

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Bibliographic Details
Main Authors: Parthasarathy, S, Wieland, E, Steinberg, D
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC286618/
https://ncbi.nlm.nih.gov/pubmed/2536929
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