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A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

Oxidative modification of low density lipoprotein (LDL) has been implicated as a factor in the generation of macrophage-derived foam cells in vitro and in vivo. However, the exact mechanism of LDL oxidation has not been established. The present studies show that cellular lipoxygenase activity is inv...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Parthasarathy, S, Wieland, E, Steinberg, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536929/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.1046
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