A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.
Oxidative modification of low density lipoprotein (LDL) has been implicated as a factor in the generation of macrophage-derived foam cells in vitro and in vivo. However, the exact mechanism of LDL oxidation has not been established. The present studies show that cellular lipoxygenase activity is inv...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.1046 |
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