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Design, Synthesis, and Docking Studies of Peptidomimetics based on HER2-Herceptin Binding Site with Potential Antiproliferative Activity Against Breast Cancer Cell lines

Epidermal growth factor receptor (EGFR) kinase and the related human epidermal growth factor receptor-2 (HER2, ErbB2) are two growth factor receptors that have implications in cancer. The overexpression or activation of HER2 occurs frequently in breast, ovarian, and lung cancers, making it an import...

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Bibliografiska uppgifter
Huvudupphovsmän: Satyanarayanajois, Seetharama, Villalba, Stephanie, Jianchao, Liu, Lin, Go Mei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866155/
https://ncbi.nlm.nih.gov/pubmed/19703026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00855.x
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