Inhibition of CtBP1 activity by Akt-mediated phosphorylation

Pc2 (Cbx4) is a member of the chromobox family of polycomb proteins, and is a SUMO E3 ligase for the transcriptional corepressor, CtBP1. Here we show that both CtBP1 and Pc2 are phosphorylated by the kinase Akt1, which is activated by growth factor signaling via the PI3-kinase pathway. In the presen...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Merrill, Jacqueline C., Kagey, Michael H., Melhuish, Tiffany A., Powers, Shannon E., Zerlanko, Brad J., Wotton, David
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866129/
https://ncbi.nlm.nih.gov/pubmed/20361981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.048
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker