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Phosphorylation of CtBP1 by cAMP-dependent Protein Kinase Modulates Induction of CYP17 by Stimulating Partnering of CtBP1 and 2

In the human adrenal cortex, the peptide hormone adrenocorticotropin (ACTH) directs cortisol and adrenal androgen biosynthesis by activating a cAMP/cAMP-dependent protein kinase (PKA) pathway. Carboxyl-terminal binding protein 1 (CtBP1) is a corepressor that regulates transcription of the CYP17 gene...

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Bibliografske podrobnosti
Main Authors: Dammer, Eric B., Sewer, Marion B.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730192/
https://ncbi.nlm.nih.gov/pubmed/18184656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708432200
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